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receptor actions

Toward Understanding Ibogaine

December 8, 2014 by admin Leave a Comment

First Posted 12/30/2013 Paul Dessauer, Outreach Coordinator at WASUA, the Western Australian Substance Users’ Association, often adds insight to issues that come up on my blog.  He shared a few comments in response to my post about ibogaine, and at my request gave permission to post his remarks here. His comments include a summary of … [Read more…]

Posted in: Education, pharmacology, receptor actions, treatment Tagged: ibogaine clinic, ibogaine treatment for addiction, opioid dependence, rapid detox

A Letter from Drug Court

November 5, 2014 by admin Leave a Comment

I recently received a note from an area drug court, asking for help tapering one of my patients off buprenorphine. The patient came to me 4 years ago after being treated for a congenital pain condition.  He had been treated with 150 mg of methadone per day, becoming dependent on the medication after taking it … [Read more…]

Posted in: Addiction, Buprenorphine, Chronic pain, Legal, pharmacology, receptor actions, Suboxone, treatment Tagged: buprenorphine and sobriety, can PO force stopping Suboxone, drug court stops suboxone, Suboxone

Wasting Resources on Suboxone

October 24, 2014 by admin Leave a Comment

Originally posted 1/26/2013 Readers of this blog know that I have often questioned whether there is any clinical difference between Suboxone and generic buprenorphine.  Naloxone is an opioid-blocking chemical added to buprenorphine, supposedly in order to reduce intravenous diversion of the medication.  The combination of buprenorphine plus naloxone is branded as Suboxone. I’ve pointed out over … [Read more…]

Posted in: Addiction, Buprenorphine, pharmacology, Public policy, receptor actions, Suboxone, Subutex Tagged: Buprenorphine abuse, effects of naloxone, suboxone cost, suboxone diversion and naloxone, suboxone vs buprenorphine

Withdrawal from Suboxone or Buprenorphine

September 23, 2012 by admin 1 Comment

I received a question from a reader about withdrawal symptoms from stopping buprenorphine. My answer has relevance to opioid withdrawal in general, and to a common misconception about the duration of withdrawal symptoms. The message: Basically I quit Suboxone about 18 days ago. When I decided to quit I was taking about 8 to 12mgs per day. I … [Read more…]

Posted in: Addiction, Buprenorphine, Clean Enough, pharmacology, receptor actions, Suboxone, tolerance, Withdrawal Tagged: how long does suboxone withdrawal last, suboxone half life, Suboxone taper, Suboxone withdrawal

A Save with Suboxone?

September 21, 2012 by admin Leave a Comment

I’d like to share a recent email exchange with a reader. The post is long, but there are several interesting aspects to the discussion. I’ve removed the conversational parts, as well as the identifying information. The initial message: I was an intravenous heroin user for three years. After treatment I was able to stay clean … [Read more…]

Posted in: 12 steps, Addiction, Buprenorphine, Clean Enough, pharmacology, receptor actions, recovery, Suboxone, tolerance Tagged: inject buprenorphine, inject Suboxone, overdose, precipitated withdrawal, Suboxone reverse overdose

Kratom, Recovery, Elections

August 30, 2012 by admin Leave a Comment

I received a question about Kratom, and searched for a earlier post about that plant/substance.  That post came shortly after Obama’s inauguration, after someone wrote to compare his experience at that event to his experience taking opioids.  Funny how every ‘high’ has its own ‘morning after!’ That Post: On a message board called ‘opiophile’, a … [Read more…]

Posted in: Addiction, Buprenorphine, Clean Enough, pharmacology, Psychodynamics, receptor actions, recovery, Suboxone Tagged: Addiction, Kratom, Obama, opioid dependence, recovery, Suboxone

Post-op Pain on Suboxone

August 8, 2012 by admin 2 Comments

I often receive emails from patients on buprenorphine (or Suboxone) who are preparing for surgery or other painful medical procedures. Ideally in such cases, the surgeon would have a discussion with the person prescribing buprenorphine, in order to coordinate the plan for treating postoperative pain. In practice such discussions don’t seem to take place, leaving … [Read more…]

Posted in: Acute Pain, Addiction, Buprenorphine, Education, receptor actions, Suboxone, surgery, tolerance Tagged: Buprenorphine, opioid dependence, post-op pain, Suboxone, Suboxone maintenance, surgery, tolerance

Treating Depression with Opioids?

June 13, 2012 by admin 5 Comments

I received this message today: Hi, you probably answer this quite a bit. I’ve been depressed for as long as i can remember. Ive been on the ssris, snris, amphetamines and methylphenadate but none of these have worked as well as opiates. (Certainly short term,I don’t take for long periods of time). But have you … [Read more…]

Posted in: Addiction, Buprenorphine, Mood, receptor actions, treatment Tagged: Buprenorphine, depression, ect, maoi, SSRI, Suboxone, treatment-resistant depression
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