Many patients taking buprenorphine live in fear of a dark world around the corner where they will have to taper off the medication. They see horror stories on YouTube posted by people who, for some reason, abruptly stopped the medication and kept a video log of their experiences. My own Read more…
In the last post we discussed some of the misconceptions about tapering off opioids. Today we will discuss a couple basic principles, and then describe the approach I recommend for my patients tapering off buprenorphine. Tapering off Suboxone is not impossible. Opioids act at receptors that normally bind endorphins, which Read more…
Today on SuboxForum people were writing about their experiences with different buprenorphine formulations. Doctors occasionally have patients who prefer brand medications over generics, but buprenorphine patients push brand-loyalty to a different level. The current thread includes references to povidone and crospovidone, compounds included in most medications to improve bioavailability. Some Read more…
This morning I responded to a woman at SuboxForum. Her baby was taken to the NICU for ‘withdrawal’, which is better identified as neonatal abstinence syndrome. She said that the baby is eating well, but there is concern that the baby sleep only 2 hours at a stretch. The baby Read more…
A post on the Forum asked about the best remedies for opioid withdrawal. I will review the medications and other treatments for opioid withdrawal that I have heard discussed by physicians or by people on the internet. Hopefully readers will leave comments about medications or approaches that they have found Read more…
First Posted 2/6/2014 A few weeks ago I wrote about the differing standards of care for women who deliver babies while treated with buprenorphine for opioid dependence. Some hospitals require newborns exposed to buprenorphine to stay in the neonatal ICU for arbitrary length of time. Intravenous infusions of opioid agonists Read more…
First Posted 2/1/2014 The topic of newborn abstinence syndrome from buprenorphine provokes strong emotions. Expectant mothers anticipate harsh attitudes from doctors and nurses. They worry that their use of buprenorphine will cause their babies to suffer from withdrawal. They hear about the experiences of women reported to CPS after delivery, Read more…
First Posted 12/15/2013 People know my bias—that buprenorphine is best-considered a chronic, perhaps life-long treatment for a chronic, life-long disease. That said, I am aware of how many people out there are convinced that they need to be ‘off everything,’ no matter the misery opioids have caused in their lives. Read more…
First posted 11/11/2012 In my last post, I wrote about the work-up of a patient who experiences symptoms similar to opioid withdrawal that start about an hour after each dose of Suboxone. We decided that the symptoms were signs of withdrawal—i.e. reduced activity of mu-opioid pathways—and that the symptoms were Read more…
I received a question from a reader about withdrawal symptoms from stopping buprenorphine. My answer has relevance to opioid withdrawal in general, and to a common misconception about the duration of withdrawal symptoms. The message: Basically I quit Suboxone about 18 days ago. When I decided to quit I was taking about Read more…
I received the following question earlier today: Hello Dr. Junig, I am opiate dependent or rather an opiate addict. I want to seek treatment because I can’t continue this life style. I have questions about treatment. Do I have to be in full withdrawals when I go to see a Read more…
One of the top search terms for Suboxone relates to pregnancy, and fear that the baby will experience withdrawal; official name ‘neonatal abstinence syndrome.’ I wrote this post a couple years ago, and I think it is worth reposting. Since the first time around, several studies have shown that withdrawal symptoms Read more…