Humana Health Insurance recently revised their guidelines to ultimately reduce the number of scripts for Suboxone that they will cover.  I am in the process of writing the Humana Grievance Department a letter to regain coverage for a patient who was doing very well on the medication.  To provide context, last week I learned of a former patient who had stopped buprenorphine for his own reasons, who passed away a few months later from on overdose of heroin.  And then this morning a patient told me about her nephew, who at the age of 16 is in a coma after an overdose yesterday.
Buprenorphine has the power to prevent these and other deaths from opioid dependence.  But patients must have access to the medication.  Many barriers exist;  doctors are reluctant to prescribe, afraid of their practices being open to random DEA audits, unwilling to take on the additional paperwork, or not interested in attracting an ‘unsavory element’ to their practices.  And buprenorphine-based medications are too expensive.  A cost of $6-$12 per day sound reasonable for a life-saving medication, but $360 per month is a large expense for someone with piles of debt, trying to make a new start.
Then there is insurance. This is a case where good policy from insurers will literally save thousands of lives.  But Humana, by playing doctor, will do the opposite — i.e. cause the deaths of many people.  I’m sure this sounds like an exaggeration– like I must be using scary words to make a point?   I wish that were the case!  Humana is playing with just enough knowledge of science to deny claims– and in THIS situation, make no mistake– the result will be dead teenagers.  Don’t kid yourselves, Humana.
This gets a little complicated…  and while I think of it, please consider forwarding this to your local newspaper, just in case somebody with access to the press wants to save some lives.
The patient of reference has been doing well on buprenorphine for a couple years.  In January, Humana changed their policies such that the medication is no longer covered.  The patient cannot afford to purchase the medication out-of-pocket– after all, that is why he pays for a good health insurance policy!    Humana didn’t just remove buprenorphine completely, as that would have resulted in lawsuits that they would have clearly lost.  Instead, they used various drug interactions to make people ineligible for the medication, under the guise of ‘good medicine.’  The problem with this approach is that we docs know that nowadays, virtually every medication out there interacts with other medications.  We all have computer programs or reference texts to quickly sort out these interactions.  And when interactions are found, we don’t just drop the medication; we use our knowledge of biochemistry and pharmacology to prescribe safely– sometimes with different medications, and sometimes with different dosages of the same medications.  That is why medical school lasts four years!
The denial states ‘to meet medical necessity guidelines for coverage, the member must meet the following criteria:  member is not concurrently using ANY narcotic painkillers, methadone, azole antifungals, protease inhibitors, macrolide antibiotics, benzodiazepines, cimetidine, or sodium oxybate.  This coverage determination was based on the Humana Pharmacy and Therapeutics Buprenorphine Containing Products Coverage Policy.
I will paste my appeal letter to the insurer below;  the letter will explain my problem with the insurer’s policy.
Dear Medical Director,
I am writing to appeal the denial of coverage for buprenorphine for maintenance treatment of opioid dependence for a patient in my psychiatric practice, Mr.  XXXXXXX. Mr. XXXXXXX has been treated using buprenorphine for the past year, and has done well with this treatment, with no episodes of relapse.
The denial letter includes what is described as Humana’s Pharmacy and Therapeutics Buprenorphine-Containing Products Coverage Policy, but does not specifically identify the reason for my patient’s denial.  For that reason, I will address several issues that are included under your stated policy, after first addressing an issue that is not part of the policy, i.e. length of treatment.
Length of coverage for buprenorphine maintenance
I assume that coverage is not being denied for reasons related the period of time for treatment with buprenorphine. More and more studies establish that buprenorphine should be considered as a maintenance medication. I personally am aware of several deaths of people with opiate dependence after their discontinuation of buprenorphine. I understand the temptation to think that at some point, people should do well without the medication. But research has clearly shown that opioid dependence is a chronic condition that warrants chronic treatment.
The Humana Pharmacy and Therapeutics Buprenorphine-Containing Products Coverage Policy
I am well-versed with treatment using buprenorphine. I understand the fear of respiratory depression from combining benzodiazepines and opioids. I am familiar with drug/drug interactions caused by effects of some medications on hepatic enzymes. These and other issues are commonly considered and managed when prescribing medications for other disease processes. I would hope that physicians are allowed the same discretion and clinical judgment when treating patients with addictions, as when treating other conditions. The issues of drug/drug interaction and additive respiratory effects should not be considered absolute contraindications—particularly given the lack of other effective treatments for opioid dependence, and the ease with which such issues can be managed by a knowledgeable physician.
The danger of combining benzodiazepines with buprenorphine occurs when a patient is not tolerant to the mu-receptor effects of buprenorphine, and is given an additional respiratory depressant. Once a person has become tolerant to buprenorphine, the danger from respiratory depression from benzodiazepines becomes the same as in a person not taking buprenorphine. I have testified in two cases of deaths from buprenorphine and benzodiazepines; in both cases the person had no tolerance to opioids or to benzodiazepines. Even in the absence of full tolerance, combined use requires consideration but is not an absolute contraindication.
I do not know if your policy considers zolpidem (Ambien) to be a benzodiazepine; the molecule has actions similar to benzodiazepines at GABA receptors, but zolpidem is not a benzodiazepine, as it lacks the benzene and diazepine rings that define the benzodiazepine class of molecules.  At any rate, non-benzodiazepine GABA hypnotics can be used safely in people taking buprenorphine for the same reasons as described for benzodiazepines.
When considering using any potentially-addictive medication in a patient with a history of addiction, consideration must be given to the risk of cross-addiction. This consideration applies to the use of benzodiazepines and other sedative/hypnotics.  Deliberations over the risk to benefit ratio in such circumstances has always been part of the work of physicians treating addictive and psychiatric disorders. This need for deliberation does not imply an absolute contraindication to concomitant use of buprenorphine and benzodiazepines.
Opioid Agonists and Pain
Your policy states that buprenorphine will not be allowed in patients receiving narcotic analgesics. But from time to time, patients on buprenorphine maintenance will require surgery, will suffer from trauma, or will have painful dental procedures. The treatment of acute and chronic pain in patients on buprenorphine has been studied extensively, and a significant body of literature supports the use of opioid agonists in people taking buprenorphine. As an aside, combining buprenorphine with opioid agonists works so well that I have no doubt that combination treatment using buprenorphine and agonists will eventually be recognized as the best way to administer opioid analgesia while reducing the risk of dependence.
Your buprenorphine policy allows no opioid analgesia for patients on buprenorphine who become injured or require surgery. What do the writers of your policy expect people on buprenorphine to do in the case of surgery? If a patient has pain that requires an opioid agonist, will that patient lose insurance coverage for the only truly effective treatment for opioid dependence?
I have treated post-surgical pain for patients on buprenorphine using opioid agonists as recommended in the literature. I have included an excellent review article that describes the technique.  The article includes references for studies of combining buprenorphine with opioid agonists for pain management.
I do not plan to prescribe opioid agonists for Mr. XXXXXXX.  But the writers of your buprenorphine policy should be aware that there are patients who require long-term opioid analgesia, who at the same time benefit from an anti-craving medication. It is simplistic and scientifically naïve to believe that one should automatically disqualify the other.
I ask for a resumption of coverage for the prescription for buprenorphine for Mr. XXXXXXX. If that coverage is not provided, I ask for the specific reason for disqualification. I will continue to aggressively advocate for Mr. XXXXXXX, and for his right for treatment under the terms of his policy. He is already struggling with a potentially fatal illness. At the very least, he deserves coverage for the one effective medication for his condition.
I’ll let readers know how things turn out.


thankfulmom · January 30, 2011 at 9:18 am

This is an example of the insurance company trying to deny payment. I work in the pharmaceutical field and I can tell you (but you know already) that this happens all of the time. I also think it is an example of people treating addicts badly. I wonder if they would feel the same if the med was prescribed for someone who became addicted as a soldier with a severe wound or in a traffic accident with a broken vertebrae. Before anyone can participate in these decisions they should spent a few days in rehab and a few in the emergency rooms . They should see the families and hear their pain. They need to know that we love our addicts just like they love their perfect sons.

moman · January 30, 2011 at 3:48 pm

Seems inevitable with the idiotic healthcare law looming. Too many folks fell for all the lies, and even now seek to block its repeal. The whole house of cards in crashing down, so they forced another Ponzi scheme down everyone’s throat!

tlily2001 · February 20, 2011 at 10:51 pm

How do I know if I’m an addict or just suffer from chronic pain? I have to have surgery but I’m on 6mg of suboxone. I don’t like the side effects which include weight loss and a need to sleep for 12 -14 hours. Should I detox from Suboxone first? Am I craving opiates when I want off of everything so that I can see if I hurt more than
the flare ups that I now have quite often?
Here’s my story. I’ve had chronic pain since a fall on ice in 2005. This led to 3 failed rotator cuff sugeries and cervical fusion and a failed hemi-shoulder replacement. I was becoming fearful of using the prescribed amount of Percocet as it was losing it’s power after 2yrs of use. I sought a pm doc who really scared me into being admitted as I was also on Soma which had been prescribed after the cervical fusion. I did not research this doc as I was new to pain management.. This doc was previously a drug addict and lost his license for a while. He came back and became an awesome doctor for addicts. He never saw me or wrote orders for my 2 day stay. He had put me on Suboxone, which I had not heard of prior to being admitted. He talked to me, always accusingly. He did not believe me at any time. I finally got my sister to advocate for me and that ended my nightmare with him.
I waited 2 months to get into this new doc. My sister went with me the first time. He was in a hurry but apologized and said that he would spend more time getting to know me. My “good side” had started hurting BADLY before the second appt. I thought it was coming fro the neck. So I got in to see the neuro surgeon. He ordered MRIs of the neck and left shoulder. He also ordered an EMG of upper quadrants. I have a full thickness tear of the cuff and severe carpal tunnel on one side

bool452 · March 2, 2011 at 1:05 pm

I unfortunately picked Humana/Walmart as my Medicare Part D prescription coverage. Humana Has made it a nightmare to get suboxone approved and I have given up. I’m going to try tapering off slowly (I’m scared – I’ve heard sometimes tapering doesn’t seem to help). They have denied coverage mainly because subutex exists. I don’t think my doctor will let me have subutex. There are other problems too, like my doctor makes me to 12 AA meetings a month and get a little sheet signed. I am 56 years old and I feel very foolish waiting in line for my little paper at a meeting where people on suboxone are not wanted. It’s just too hard to get this drug. I’m on 2mg/day and feel very stable. I’d love to stay on longer but it’s not possible. I think I’ll be ok though.

Carlos · April 8, 2017 at 7:03 pm

I am on medicare. I was with AARP.United Health was managing my medication with no problem.
Since Jamuary or so I began to receive letter from Humana. I never made the change.
Buy now humana bas been going for three dayz playong with my prior approval for suboxone.
What happened I didn’t request the change from united health to humana.

    Jeffrey Junig MD PhD · April 9, 2017 at 8:17 pm

    That’s a question for the insurance company covering you. If you have a new insurer, you received a new health insurance card in the mail. You should call the customer service number on the back of that card, and ask what happened.
    It could be that AARP changed the company that provides benefits under their plan. I don’t know, though, if that’s true– you’ll have to make the call and ask.

Patty · December 9, 2017 at 10:44 am

What a shame that Humana is denying paying for a drug that saving lives shame on you

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