Buprenorphine Overdose After Naltrexone Treatment

Naltrexone induces mu-receptor hypersensitivity.  Buprenorphine’s protective ‘ceiling effect’ may not prevent overdose in patients with this ‘reverse tolerance’. A new patient described his recent history of respiratory failure several days into buprenorphine treatment.  He was told by his doctors that he experienced an allergic reaction to Suboxone. The rarity of Read more…

Sick When Starting Suboxone: Abres Los Ojos!

An interesting case from a reader: Thanks Doc for your efforts. I appreciate you. I am a four year hydrocodone addict 55 years old. I became addicted when I used the drug for an injured cervical disc. A couple of years ago I found out about suboxone and got in Read more…