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Buprenorphine Overdose After Naltrexone Treatment

February 14, 2017 by admin 7 Comments

Naltrexone induces mu-receptor hypersensitivity. Buprenorphine’s protective ‘ceiling effect’ may not prevent overdose in patients with this ‘reverse tolerance’. A new patient described his recent history of respiratory failure several days into buprenorphine treatment. He was told by his doctors that he experienced an allergic reaction to Suboxone. The rarity of buprenorphine or naloxone allergy led … [Read more…]

Suboxone Detox is a Sucker’s Bet

November 20, 2014 by admin Leave a Comment

First Posted 10/6/2013 I attended the US Psychiatric and Mental Health Congress meeting last week and actually attended the meetings (the event was held in Las Vegas), but I was disappointed by the absence of lectures about addiction. There are other mental health groups geared more toward addiction, but one would think that psychiatry would maintain … [Read more…]